Among infected usually dominated by people of young age (30-39 years). The ratio of men and women, according to the research Center USA is 10-15: 1.

There are several stages of disease.

The initial stage of disease (stage I) half of the infected are not manifested by any symptoms. Patients do not make any complaints. 50 infected after about 5-6 weeks after infection develops acute febrile phase with fever, General weakness, sweating at night, lethargy, loss of appetite, nausea, myalgia, arthralgia, headache, sore throat, diarrhea, lymphadenopathy, diffuse maculopapular rash, flaking of skin, worsening of seboreynogo dermatitis, recurrent herpes.

Acute diffuse glomerulonephritis is characterized by three main symptoms: edema, hypertension and urinary.

The disease usually develops acutely. Patients report fever, weakness, preferential swelling of the face, headache, decreased urine output.

An early sign of the disease are swelling. They are found in 80-90 patients are located primarily on the face and create together with the pale skin typical "face nefritika". Often the fluid accumulates in the cavities (pleural, peritoneal and pericardial cavity). The weight gain due to the swelling can reach in a short time 15-20 kg or more. Usually after 2-3 weeks, the swelling disappear.

The disease manifests after 1-6 weeks after streptococcal infection.
Classic signs of acute nephritis:
- Hematuria (100). Gross hematuria occurs in 30 cases (urine color of meat slops).
- Swelling (85). The most characteristic swelling of the face (especially the eyelids) from the second half of the day, and also feet and lower legs in the evening.
- Arterial hypertension (82)
- Hypocomplementemia (content NW) of 83 cases.
- Oligoanuria (52) in combination with thirst.
Other attributes:
- The fever (rare).
- Anorexia, nausea, vomiting, headache, slabost.
- Lower back pain.
- Pain in the abdomen.
- Weight gain.
Signs of an infectious respiratory disease (including acute tonsillitis, pharyngitis).
Signs of scarlet fever.
- Signs of impetigo.

In the course of acute renal failure is divided into four periods or stages: 1) shock, 2) oligoanuria, 3) recovery of diuresis with the initial phase of diuresis and polyuria phase, and finally, 4) the recovery period. In the first period the most pronounced symptoms of the underlying disease that led to acute renal failure and shock. Marked tachycardia, lowering blood pressure, which, however, may be transient. In the period of oligoanuria decreases or stops altogether of urine formation.

One of the most common causes of endometriosis. However, pain in this pathology possible throughout the menstrual cycle and may increase 2-3 days before menstruation. They are often not cramping and aching radiating to the region of the rectum. Pain is not accompanied by the "autonomic storm" (vomiting, nausea, sweating, diarrhea). Gynecology, depending on the location and distribution of endometrioid heterotopias determine the thickening and tenderness of the uterosacral ligaments, pain when moving the cervix, the increase of the uterus, changes in the uterus and ovaries before menstruation and decrease thereafter.

Hyperprolactinemia is accompanied by a change of ovarian function which can lead to anovulation, luteal phase deficiency, disorders of the menstrual cycle according to the type of oligomenorrhea or secondary amenorrhea.

In 67 women with hyperprolactinemia may occur galactorrhea, which does not correlate with prolactin levels. Under normal prolactin levels can also be galactorrhea, which is associated with hypersensitivity of the receptors of prolactin to its normal level or with high biological activity of prolactin. Galactorrhea appears as in anovulation and ovulatory menstrual cycles, as well as with normal content of prolactin.

Women suffering from candidiasis of vulva and vagina, mainly complain of itching and whites mixed with cheesy-kroshkovidny inclusions, hence the name "thrush". The discharge may be thick, white, yellowish-greenish, depending on the severity of the process. The smell is usually sour, unpleasant. Itching causes a lot of anxiety patients, sometimes making them incapacitated and severely straining the nervous system, as it almost never slows down, is worse at night and leads to traumatizing the mucosa of the vulva due to scratching. Sometimes patients note pain when urinating, and a burning sensation.

Ectopia of the cervix involves the displacement of cylindrical epithelium on the vaginal portion of the cervix. To denote ectopia long used the term "pseudo". Isolated acquired and congenital ectopia (the pseudo).

In the opinion of many clinicians-nephrologists, there are two types of chronic glomerulonephritis: primary and secondary chronic. To primary chronic glomerulonephritis are those cases that occur without preceding acute glomerulonephritis, i.e. from the beginning (primary) glomerulonephritis becomes chronic.

Course and clinical picture of chronic pyelonephritis depend on many factors, including the location of inflammation in one or both kidneys (unilateral or bilateral), the prevalence of the pathological process, the presence or absence of obstacles to the current of the urine in the urinary tract, the effectiveness of previous treatment, possible comorbidities.

The main symptom of vaginitis, based on which can sometimes diagnose are vaginal discharge, which in some cases are liquid, while others - purulent character. Patients coming to the clinic, complain of the sensation of itching in the vaginal area and vulva, on the impossibility of intercourse because of severe pain.

Generally accepted classification of diabetic angiopathy does not exist. They are constructed mainly on the basis of individual clinical manifestations of vascular lesions (diabetic retinopathy, nephropathy), or are based mainly on morphological changes of the organs.